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cpp/hamming/README.md
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# Hamming
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Write a program that can calculate the Hamming difference between two DNA strands.
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A mutation is simply a mistake that occurs during the creation or
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copying of a nucleic acid, in particular DNA. Because nucleic acids are
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vital to cellular functions, mutations tend to cause a ripple effect
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throughout the cell. Although mutations are technically mistakes, a very
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rare mutation may equip the cell with a beneficial attribute. In fact,
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the macro effects of evolution are attributable by the accumulated
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result of beneficial microscopic mutations over many generations.
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The simplest and most common type of nucleic acid mutation is a point
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mutation, which replaces one base with another at a single nucleotide.
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By counting the number of differences between two homologous DNA strands
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taken from different genomes with a common ancestor, we get a measure of
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the minimum number of point mutations that could have occurred on the
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evolutionary path between the two strands.
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This is called the 'Hamming distance'.
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It is found by comparing two DNA strands and counting how many of the
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nucleotides are different from their equivalent in the other string.
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GAGCCTACTAACGGGAT
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CATCGTAATGACGGCCT
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^ ^ ^ ^ ^ ^^
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The Hamming distance between these two DNA strands is 7.
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# Implementation notes
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The Hamming distance is only defined for sequences of equal length. This means
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that based on the definition, each language could deal with getting sequences
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of equal length differently.
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## Getting Started
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Make sure you have read the [getting started with C++](http://help.exercism.io/getting-started-with-cpp.html)
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page on the [exercism help site](http://help.exercism.io/). This covers
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the basic information on setting up the development environment expected
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by the exercises.
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## Passing the Tests
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Get the first test compiling, linking and passing by following the [three
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rules of test-driven development](http://butunclebob.com/ArticleS.UncleBob.TheThreeRulesOfTdd).
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Create just enough structure by declaring namespaces, functions, classes,
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etc., to satisfy any compiler errors and get the test to fail. Then write
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just enough code to get the test to pass. Once you've done that,
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uncomment the next test by moving the following line past the next test.
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```C++
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#if defined(EXERCISM_RUN_ALL_TESTS)
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```
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This may result in compile errors as new constructs may be invoked that
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you haven't yet declared or defined. Again, fix the compile errors minimally
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to get a failing test, then change the code minimally to pass the test,
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refactor your implementation for readability and expressiveness and then
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go on to the next test.
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Try to use standard C++11 facilities in preference to writing your own
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low-level algorithms or facilities by hand. [CppReference](http://en.cppreference.com/)
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is a wiki reference to the C++ language and standard library. If you
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are new to C++, but have programmed in C, beware of
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[C traps and pitfalls](http://www.slideshare.net/LegalizeAdulthood/c-traps-and-pitfalls-for-c-programmers).
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## Source
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The Calculating Point Mutations problem at Rosalind [view source](http://rosalind.info/problems/hamm/)
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